is home to many of the world's leading casino companies and perhaps the most widely known gambling destination in the world: Las Vegas, Nevada. have remained relatively consistent, with 466 commercial and 515 tribal casinos operating nationwide in 2021. Over the last few years, the number of commercial and tribal casinos in the U.S. Whether land-based, on riverboats, or at racetracks, casinos are among the most popular gambling establishments in the United States. Casinos in the United States: Placing all bets on Las Vegas?